Method
bis-indole synthesis from 2-iodoanilines and terminal diynes via sequential Sonogashira and cyclization reaction
- Description:
- Synthesis of analogs of types 5 and 6 from the paper
- Subjects:
- Keywords:
- indole, synthesis, Sonogashira, palladium, TBAF, CuI, bis-indole
1 user recommends this method
From: Convenient Indole Synthesis from 2-Iodoanilines and Terminal Alkynes by the Sequential Sonogashira Reaction and the Cyclization Reaction Promoted by Tetrabutylammonium Fluoride (TBAF)
by: Suzuki, Naoyuki; Yasaki, Sakura; Yasuhara, Akito; Sakamoto, Takao
CHEMICAL & PHARMACEUTICAL BULLETIN, 2003, 51(10), pp. 1170-1173
DOI: 10.1248/cpb.51.1170
How Well Does this Method Work?
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Under Identical Circumstances to
the Publication
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Under Different Circumstances than
the Publication
4.0
- 0 Did not work at all for me 1 My results were much worse 2 My results were worse 3 Modifications were required 4 My results were as good or better
Method Evaluations
| Date | User | Recommend? | Under Identical Circumstances | Under Different Circumstances | Additional Comments | Is This Eval Useful? | View |
|---|---|---|---|---|---|---|---|
| 2010-07-10 | cjdocken | |
- | 4 | Y | - |
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