Convenient Indole Synthesis from 2-Iodoanilines and Terminal Alkynes by the Sequential Sonogashira Reaction and the Cyclization Reaction Promoted by Tetrabutylammonium Fluoride (TBAF)
by: Suzuki, Naoyuki; Yasaki, Sakura; Yasuhara, Akito; Sakamoto, Takao
CHEMICAL & PHARMACEUTICAL BULLETIN, 2003, 51(10), pp. 1170-1173
DOI: 10.1248/cpb.51.1170
Methods
bis-indole synthesis from 2-iodoanilines and terminal diynes via sequential Sonogashira and cyclization reaction
- Description:
- Synthesis of analogs of types 5 and 6 from the paper
- Subjects:
- Chemistry > Medicinal & Pharmaceutical Chemistry, Organic Chemistry, Organometallic Chemistry
- Keywords:
- indole synthesis Sonogashira palladium TBAF CuI bis-indole
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